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Binding Studies of AICAR and Human Serum Albumin by Spectroscopic, Theoretical, and Computational Methodologies

The interactions of small molecule drugs with plasma serum albumin are important because of the influence of such interactions on the pharmacokinetics of these therapeutic agents. 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) is one such drug candidate that has recently gained attention for...

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Detalles Bibliográficos
Autores principales: Hashempour, Shokoufeh, Shahabadi, Nahid, Adewoye, Aishat, Murphy, Brennen, Rouse, Camaray, Salvatore, Brian A., Stratton, Christopher, Mahdavian, Elahe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699360/
https://www.ncbi.nlm.nih.gov/pubmed/33228044
http://dx.doi.org/10.3390/molecules25225410