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Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells

The amyloid-β precursor protein (APP) is a ubiquitous membrane protein often associated with Alzheimer’s disease (AD) and cerebral amyloid angiopathy (CAA). Despite its role in the development of the pathogenesis, APP exerts several physiological roles that have been mainly investigated in neuronal...

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Detalles Bibliográficos
Autores principales: Ristori, Emma, Cicaloni, Vittoria, Salvini, Laura, Tinti, Laura, Tinti, Cristina, Simons, Michael, Corti, Federico, Donnini, Sandra, Ziche, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699411/
https://www.ncbi.nlm.nih.gov/pubmed/33228083
http://dx.doi.org/10.3390/cells9112506