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Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells
The amyloid-β precursor protein (APP) is a ubiquitous membrane protein often associated with Alzheimer’s disease (AD) and cerebral amyloid angiopathy (CAA). Despite its role in the development of the pathogenesis, APP exerts several physiological roles that have been mainly investigated in neuronal...
Autores principales: | Ristori, Emma, Cicaloni, Vittoria, Salvini, Laura, Tinti, Laura, Tinti, Cristina, Simons, Michael, Corti, Federico, Donnini, Sandra, Ziche, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699411/ https://www.ncbi.nlm.nih.gov/pubmed/33228083 http://dx.doi.org/10.3390/cells9112506 |
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