Remyelination-Promoting DNA Aptamer Conjugate Myaptavin-3064 Binds to Adult Oligodendrocytes In Vitro

We previously applied Systematic Evolution of Ligands by EXponential enrichment (SELEX) technology to identify myelin-specific DNA aptamers, using crude mouse central nervous system myelin as bait. This selection identified a 40-nucleotide aptamer (LJM-3064). Multiple biotinylated LJM-3064 molecules...

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Detalles Bibliográficos
Autores principales: Fereidan-Esfahani, Mahboubeh, Yue, Wei Ying, Wilbanks, Brandon, Johnson, Aaron J., Warrington, Arthur E., Howe, Charles L., Rodriguez, Moses, Maher, Louis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699424/
https://www.ncbi.nlm.nih.gov/pubmed/33228043
http://dx.doi.org/10.3390/ph13110403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699424/
https://www.ncbi.nlm.nih.gov/pubmed/33228043
http://dx.doi.org/10.3390/ph13110403

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