Cargando…

Remyelination-Promoting DNA Aptamer Conjugate Myaptavin-3064 Binds to Adult Oligodendrocytes In Vitro

We previously applied Systematic Evolution of Ligands by EXponential enrichment (SELEX) technology to identify myelin-specific DNA aptamers, using crude mouse central nervous system myelin as bait. This selection identified a 40-nucleotide aptamer (LJM-3064). Multiple biotinylated LJM-3064 molecules...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fereidan-Esfahani, Mahboubeh, Yue, Wei Ying, Wilbanks, Brandon, Johnson, Aaron J., Warrington, Arthur E., Howe, Charles L., Rodriguez, Moses, Maher, Louis J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699424/ https://www.ncbi.nlm.nih.gov/pubmed/33228043 http://dx.doi.org/10.3390/ph13110403

Ejemplares similares

An Assay that Predicts In Vivo Efficacy for DNA Aptamers that Stimulate Remyelination in a Mouse Model of Multiple Sclerosis
por: Heider, Robin M., et al.
Publicado: (2018)

Remyelination Induced by a DNA Aptamer in a Mouse Model of Multiple Sclerosis
por: Nastasijevic, Branislav, et al.
Publicado: (2012)

PDGF is Required for Remyelination-Promoting IgM Stimulation of Oligodendrocyte Progenitor Cell Proliferation
por: Watzlawik, Jens O., et al.
Publicado: (2013)

Antibody-Mediated Oligodendrocyte Remyelination Promotes Axon Health in Progressive Demyelinating Disease
por: Wootla, Bharath, et al.
Publicado: (2015)

Optimization of a 40-mer Antimyelin DNA Aptamer Identifies a 20-mer with Enhanced Properties for Potential Multiple Sclerosis Therapy
por: Wilbanks, Brandon, et al.
Publicado: (2019)

Remyelination as Neuroprotection
por: Howe, Charles L., et al.
Publicado: (2005)

Vitamin C promotes oligodendrocytes generation and remyelination
por: Guo, Yu‐e, et al.
Publicado: (2018)

Role of exercise in the brain: focus on oligodendrocytes and remyelination
por: Maugeri, Grazia, et al.
Publicado: (2023)

Iron Metabolism in Oligodendrocytes and Astrocytes, Implications for Myelination and Remyelination
por: Cheli, Veronica T., et al.
Publicado: (2020)

A monoclonal natural human IgM protects axons in the absence of remyelination
por: Wootla, Bharath, et al.
Publicado: (2016)

Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation
por: Dierckx, Tess, et al.
Publicado: (2022)

Motor Learning Promotes Remyelination via New and Surviving Oligodendrocytes
por: Bacmeister, Clara M., et al.
Publicado: (2020)

Peroxidase proximity selection to identify aptamers targeting a subcellular location
por: Wilbanks, Brandon, et al.
Publicado: (2023)

Locomotor recovery following contusive spinal cord injury does not require oligodendrocyte remyelination
por: Duncan, Greg J., et al.
Publicado: (2018)

TMEM10 Promotes Oligodendrocyte Differentiation and is Expressed by Oligodendrocytes in Human Remyelinating Multiple Sclerosis Plaques
por: de Faria, Omar, et al.
Publicado: (2019)

In vitro analysis of the oligodendrocyte lineage in mice during demyelination and remyelination
Publicado: (1990)

Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination
por: Chen, Yongfeng, et al.
Publicado: (2017)

CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes
por: Dimas, Penelope, et al.
Publicado: (2019)

Vitamin D increases remyelination by promoting oligodendrocyte lineage differentiation
por: Gomez‐Pinedo, Ulises, et al.
Publicado: (2019)

A higher proportion of ermin-immunopositive oligodendrocytes in areas of remyelination
por: Ahmad, Intakhar, et al.
Publicado: (2021)

Immunoglobulin directly enhances differentiation of oligodendrocyte-precursor cells and remyelination
por: Li, Yaguang, et al.
Publicado: (2023)

DCX(+) neuronal progenitors contribute to new oligodendrocytes during remyelination in the hippocampus
por: Klein, Barbara, et al.
Publicado: (2020)

Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination
por: Hubler, Zita, et al.
Publicado: (2018)

Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination
por: De La Fuente, Alerie Guzman, et al.
Publicado: (2017)

Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors
por: Gautier, Hélène O. B., et al.
Publicado: (2015)

Transcription factor 7 like 2 promotes oligodendrocyte differentiation and remyelination
por: Weng, Chao, et al.
Publicado: (2017)

Stemazole Promotes Oligodendrocyte Precursor Cell Survival In Vitro and Remyelination In Vivo
por: Zhu, Yizi, et al.
Publicado: (2022)

Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response
por: Chen, Yanan, et al.
Publicado: (2023)

Fractalkine enhances oligodendrocyte regeneration and remyelination in a demyelination mouse model
por: de Almeida, Monique M.A., et al.
Publicado: (2023)

Ion-dependent conformational switching by a DNA aptamer that induces remyelination in a mouse model of multiple sclerosis
por: Smestad, John, et al.
Publicado: (2013)

Prostacyclin promotes oligodendrocyte precursor recruitment and remyelination after spinal cord demyelination
por: Takahashi, C, et al.
Publicado: (2013)

Amiloride Promotes Oligodendrocyte Survival and Remyelination after Spinal Cord Injury in Rats
por: Imai, Takeshi, et al.
Publicado: (2018)

Shikimic Acid Promotes Oligodendrocyte Precursor Cell Differentiation and Accelerates Remyelination in Mice
por: Lu, Fengfeng, et al.
Publicado: (2019)

OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease
por: Yun, Wonjin, et al.
Publicado: (2022)

p70S6 kinase regulates oligodendrocyte differentiation and is active in remyelinating lesions
por: Benardais, Karelle, et al.
Publicado: (2022)

Neural stem cells and oligodendrocyte progenitor cells compete for remyelination in the corpus callosum
por: Moyon, Sarah, et al.
Publicado: (2023)

Author Correction: Immunoglobulin directly enhances differentiation of oligodendrocyte-precursor cells and remyelination
por: Li, Yaguang, et al.
Publicado: (2023)

Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination
por: Rivera, Francisco J., et al.
Publicado: (2019)

Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination
por: Syed, Yasir A, et al.
Publicado: (2013)

The contribution of oligodendrocytes and oligodendrocyte progenitor cells to central nervous system repair in multiple sclerosis: perspectives for remyelination therapeutic strategies
por: Dulamea, Adriana Octaviana
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_e69ddjg9p93qfku7eo3cbn85k1