Cargando…

Activation of PI3K/Akt/HIF-1α Signaling is Involved in Lung Protection of Dexmedetomidine in Patients Undergoing Video-Assisted Thoracoscopic Surgery: A Pilot Study

BACKGROUND: Lung resection and one lung ventilation (OLV) during video-assisted thoracoscopic surgery (VATS) may lead to acute lung injury. Dexmedetomidine (DEX), a highly selective α(2) adrenergic receptor agonist, improves arterial oxygenation in adult patients undergoing thoracic surgery. The aim...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Linjia, Zhang, Yang, Zhang, Zhenfeng, Ding, Xiahao, Gong, Chanjuan, Qian, Yanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699453/
https://www.ncbi.nlm.nih.gov/pubmed/33262576
http://dx.doi.org/10.2147/DDDT.S276005