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Targeting Beta-Blocker Drug–Drug Interactions with Fibrinogen Blood Plasma Protein: A Computational and Experimental Study

In this work, one of the most prevalent polypharmacology drug–drug interaction events that occurs between two widely used beta-blocker drugs—i.e., acebutolol and propranolol—with the most abundant blood plasma fibrinogen protein was evaluated. Towards that end, molecular docking and Density Function...

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Detalles Bibliográficos
Autores principales: González-Durruthy, Michael, Concu, Riccardo, Vendrame, Laura F. Osmari, Zanella, Ivana, Ruso, Juan M., Cordeiro, M. Natália D. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699576/
https://www.ncbi.nlm.nih.gov/pubmed/33228181
http://dx.doi.org/10.3390/molecules25225425