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Toward the Identification of Novel Antimicrobial Agents: One-Pot Synthesis of Lipophilic Conjugates of N-Alkyl d- and l-Iminosugars

In the effort to improve the antimicrobial activity of iminosugars, we report the synthesis of lipophilic iminosugars 10a–b and 11a–b based on the one-pot conjugation of both enantiomeric forms of N-butyldeoxynojirimycin (NBDNJ) and N-nonyloxypentyldeoxynojirimycin (NPDNJ) with cholesterol and a suc...

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Detalles Bibliográficos
Autores principales: Esposito, Anna, D’Alonzo, Daniele, D’Errico, Stefano, De Gregorio, Eliana, Guaragna, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699595/
https://www.ncbi.nlm.nih.gov/pubmed/33228211
http://dx.doi.org/10.3390/md18110572