Cargando…

Bioinformatics identification and pharmacological validation of Kcnn3/K(Ca)2 channels as a mediator of negative affective behaviors and excessive alcohol drinking in mice

Mood disorders are often comorbid with alcohol use disorder (AUD) and play a considerable role in the development and maintenance of alcohol dependence and relapse. Because of this high comorbidity, it is necessary to determine shared and unique genetic factors driving heavy drinking and negative af...

Descripción completa

Detalles Bibliográficos
Autores principales: Padula, Audrey E., Rinker, Jennifer A., Lopez, Marcelo F., Mulligan, Megan K., Williams, Robert W., Becker, Howard C., Mulholland, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699620/
https://www.ncbi.nlm.nih.gov/pubmed/33247097
http://dx.doi.org/10.1038/s41398-020-01099-4