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Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy

Loss of muscle tone triggered by emotions is called cataplexy and is the pathognomonic symptom of narcolepsy, which is caused by hypocretin deficiency. Cataplexy is classically considered to be an abnormal manifestation of REM sleep and is treated by selective serotonin (5HT) reuptake inhibitors. He...

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Detalles Bibliográficos
Autores principales: Seifinejad, Ali, Li, Sha, Possovre, Marie-Laure, Vassalli, Anne, Tafti, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699625/
https://www.ncbi.nlm.nih.gov/pubmed/33247179
http://dx.doi.org/10.1038/s41467-020-19862-y