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Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy
Loss of muscle tone triggered by emotions is called cataplexy and is the pathognomonic symptom of narcolepsy, which is caused by hypocretin deficiency. Cataplexy is classically considered to be an abnormal manifestation of REM sleep and is treated by selective serotonin (5HT) reuptake inhibitors. He...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699625/ https://www.ncbi.nlm.nih.gov/pubmed/33247179 http://dx.doi.org/10.1038/s41467-020-19862-y |