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Type I toxin-antitoxin systems contribute to the maintenance of mobile genetic elements in Clostridioides difficile

Toxin-antitoxin (TA) systems are widespread on mobile genetic elements and in bacterial chromosomes. In type I TA, synthesis of the toxin protein is prevented by the transcription of an antitoxin RNA. The first type I TA were recently identified in the human enteropathogen Clostridioides difficile....

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Detalles Bibliográficos
Autores principales: Peltier, Johann, Hamiot, Audrey, Garneau, Julian R., Boudry, Pierre, Maikova, Anna, Hajnsdorf, Eliane, Fortier, Louis-Charles, Dupuy, Bruno, Soutourina, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699646/
https://www.ncbi.nlm.nih.gov/pubmed/33247281
http://dx.doi.org/10.1038/s42003-020-01448-5