Detection of KRAS G12/G13 Mutations in Cell Free-DNA by Droplet Digital PCR, Offers Prognostic Information for Patients with Advanced Non-Small Cell Lung Cancer

KRAS mutations are found in approximately one third of non-small cell lung cancer (NSCLC) patients. In this study, we aim to investigate whether KRAS G12/G13 mutant allele fraction (MAF) in cell-free DNA (cfDNA) can provide meaningful prognostic information in NSCLC. Multiplex droplet-digital PCR wa...

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Detalles Bibliográficos
Autores principales: Michaelidou, Kleita, Koutoulaki, Chara, Mavridis, Konstantinos, Vorrias, Eleftherios, Papadaki, Maria A., Koutsopoulos, Anastasios V., Mavroudis, Dimitrios, Agelaki, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699710/
https://www.ncbi.nlm.nih.gov/pubmed/33233668
http://dx.doi.org/10.3390/cells9112514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699710/
https://www.ncbi.nlm.nih.gov/pubmed/33233668
http://dx.doi.org/10.3390/cells9112514

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