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Liraglutide Activates Glucagon-Like Peptide 1 Receptor to Attenuate Hyperglycemia through Endogenous Beta-Endorphin in Diabetic Rats

Liraglutide, an acylated analog of glucagon-like peptide 1 (GLP-1), could improve glycemic control in diabetes. Moreover, endogenous opioid peptides play a role in blood sugar regulation. Since GLP-1 receptors are also expressed in extra-pancreatic tissues, this study investigates the effect of lira...

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Detalles Bibliográficos
Autores principales: Cheng, Kai-Chun, Li, Ying-Xiao, Shieh, Po-Chuen, Cheng, Juei-Tang, Hsu, Chia-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699724/
https://www.ncbi.nlm.nih.gov/pubmed/33233692
http://dx.doi.org/10.3390/ph13110407