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Liraglutide Activates Glucagon-Like Peptide 1 Receptor to Attenuate Hyperglycemia through Endogenous Beta-Endorphin in Diabetic Rats
Liraglutide, an acylated analog of glucagon-like peptide 1 (GLP-1), could improve glycemic control in diabetes. Moreover, endogenous opioid peptides play a role in blood sugar regulation. Since GLP-1 receptors are also expressed in extra-pancreatic tissues, this study investigates the effect of lira...
Autores principales: | Cheng, Kai-Chun, Li, Ying-Xiao, Shieh, Po-Chuen, Cheng, Juei-Tang, Hsu, Chia-Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699724/ https://www.ncbi.nlm.nih.gov/pubmed/33233692 http://dx.doi.org/10.3390/ph13110407 |
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