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Analysis of Human Mutations in the Supernumerary Subunits of Complex I

Complex I is the largest member of the electron transport chain in human mitochondria. It comprises 45 subunits and requires at least 15 assembly factors. The subunits can be divided into 14 “core” subunits that carry out oxidation–reduction reactions and proton translocation, as well as 31 addition...

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Detalles Bibliográficos
Autores principales: Dang, Quynh-Chi L., Phan, Duong H., Johnson, Abigail N., Pasapuleti, Mukund, Alkhaldi, Hind A., Zhang, Fang, Vik, Steven B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699753/
https://www.ncbi.nlm.nih.gov/pubmed/33233646
http://dx.doi.org/10.3390/life10110296