Isotope Fractionation during Gas Chromatography Can Enhance Mass Spectrometry-Based Measures of (2)H-Labeling of Small Molecules

Stable isotope tracers can be used to quantify the activity of metabolic pathways. Specifically, (2)H-water is quite versatile, and its incorporation into various products can enable measurements of carbohydrate, lipid, protein and nucleic acid kinetics. However, since there are limits on how much (...

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Detalles Bibliográficos
Autores principales: Downes, Daniel P., Kasumov, Takhar, Daurio, Natalie A., Wood, Neil B., Previs, Michael J., Sheth, Payal R., McLaren, David G., Previs, Stephen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699861/
https://www.ncbi.nlm.nih.gov/pubmed/33233825
http://dx.doi.org/10.3390/metabo10110474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699861/
https://www.ncbi.nlm.nih.gov/pubmed/33233825
http://dx.doi.org/10.3390/metabo10110474

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