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Tracing Metabolic Fate of Mitochondrial Glycine Cleavage System Derived Formate In Vitro and In Vivo

Folate-mediated one-carbon (1C) metabolism is a major target of many therapies in human diseases. Studies have focused on the metabolism of serine 3-carbon as it serves as a major source for 1C units. The serine 3-carbon enters the mitochondria transferred by folate cofactors and eventually converte...

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Detalles Bibliográficos
Autores principales: Tan, Yee-Ling, Sou, Nga-Lai, Tang, Feng-Yao, Ko, Hsin-An, Yeh, Wei-Ting, Peng, Jian-Hau, Chiang, En-Pei Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699879/
https://www.ncbi.nlm.nih.gov/pubmed/33233834
http://dx.doi.org/10.3390/ijms21228808