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Tracing Metabolic Fate of Mitochondrial Glycine Cleavage System Derived Formate In Vitro and In Vivo
Folate-mediated one-carbon (1C) metabolism is a major target of many therapies in human diseases. Studies have focused on the metabolism of serine 3-carbon as it serves as a major source for 1C units. The serine 3-carbon enters the mitochondria transferred by folate cofactors and eventually converte...
Autores principales: | Tan, Yee-Ling, Sou, Nga-Lai, Tang, Feng-Yao, Ko, Hsin-An, Yeh, Wei-Ting, Peng, Jian-Hau, Chiang, En-Pei Isabel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699879/ https://www.ncbi.nlm.nih.gov/pubmed/33233834 http://dx.doi.org/10.3390/ijms21228808 |
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