Sphingomyelin Deacylase, the Enzyme Involved in the Pathogenesis of Atopic Dermatitis, Is Identical to the β-Subunit of Acid Ceramidase

A ceramide deficiency in the stratum corneum (SC) is an essential etiologic factor for the dry and barrier-disrupted skin of patients with atopic dermatitis (AD). Previously, we reported that sphingomyelin (SM) deacylase, which hydrolyzes SM and glucosylceramide at the acyl site to yield their lysof...

Descripción completa

Detalles Bibliográficos
Autores principales: Teranishi, Yasuhiro, Kuwahara, Hiroshi, Ueda, Masaru, Takemura, Tadashi, Kusumoto, Masanori, Nakamura, Keiji, Sakai, Jun, Kimura, Toru, Furutani, Yasuji, Kawashima, Makoto, Imokawa, Genji, Nogami-Itoh, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699893/
https://www.ncbi.nlm.nih.gov/pubmed/33233706
http://dx.doi.org/10.3390/ijms21228789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699893/
https://www.ncbi.nlm.nih.gov/pubmed/33233706
http://dx.doi.org/10.3390/ijms21228789

Ejemplares similares