Sphingomyelin Deacylase, the Enzyme Involved in the Pathogenesis of Atopic Dermatitis, Is Identical to the β-Subunit of Acid Ceramidase

A ceramide deficiency in the stratum corneum (SC) is an essential etiologic factor for the dry and barrier-disrupted skin of patients with atopic dermatitis (AD). Previously, we reported that sphingomyelin (SM) deacylase, which hydrolyzes SM and glucosylceramide at the acyl site to yield their lysof...

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Detalles Bibliográficos
Autores principales: Teranishi, Yasuhiro, Kuwahara, Hiroshi, Ueda, Masaru, Takemura, Tadashi, Kusumoto, Masanori, Nakamura, Keiji, Sakai, Jun, Kimura, Toru, Furutani, Yasuji, Kawashima, Makoto, Imokawa, Genji, Nogami-Itoh, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699893/
https://www.ncbi.nlm.nih.gov/pubmed/33233706
http://dx.doi.org/10.3390/ijms21228789

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