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CXCL12-PLGA/Pluronic Nanoparticle Internalization Abrogates CXCR4-Mediated Cell Migration

Chemokine-induced chemotaxis mediates physiological and pathological immune cell trafficking, as well as several processes involving cell migration. Among them, the role of CXCL12/CXCR4 signaling in cancer and metastasis is well known, and CXCR4 has been often targeted with small molecule-antagonist...

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Detalles Bibliográficos
Autores principales: Pisani, Anissa, Donno, Roberto, Gennari, Arianna, Cibecchini, Giulia, Catalano, Federico, Marotta, Roberto, Pompa, Pier Paolo, Tirelli, Nicola, Bardi, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699919/
https://www.ncbi.nlm.nih.gov/pubmed/33233846
http://dx.doi.org/10.3390/nano10112304