Mitochondrial-Protective Effects of R-Phenibut after Experimental Traumatic Brain Injury

Altered neuronal Ca(2+) homeostasis and mitochondrial dysfunction play a central role in the pathogenesis of traumatic brain injury (TBI). R-Phenibut ((3R)-phenyl-4-aminobutyric acid) is an antagonist of the α(2)δ subunit of voltage-dependent calcium channels (VDCC) and an agonist of gamma-aminobuty...

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Detalles Bibliográficos
Autores principales: Kupats, Einars, Stelfa, Gundega, Zvejniece, Baiba, Grinberga, Solveiga, Vavers, Edijs, Makrecka-Kuka, Marina, Svalbe, Baiba, Zvejniece, Liga, Dambrova, Maija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700030/
https://www.ncbi.nlm.nih.gov/pubmed/33274011
http://dx.doi.org/10.1155/2020/9364598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700030/
https://www.ncbi.nlm.nih.gov/pubmed/33274011
http://dx.doi.org/10.1155/2020/9364598

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