Fetal Hemoglobin in Sickle Hemoglobinopathies: High HbF Genotypes and Phenotypes

Fetal hemoglobin (HbF) usually consists of 4 to 10% of total hemoglobin in adults of African descent with sickle cell anemia. Rarely, their HbF levels reach more than 30%. High HbF levels are sometimes a result of β-globin gene deletions or point mutations in the promoters of the HbF genes. Collecti...

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Detalles Bibliográficos
Autor principal: Steinberg, Martin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700170/
https://www.ncbi.nlm.nih.gov/pubmed/33238542
http://dx.doi.org/10.3390/jcm9113782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700170/
https://www.ncbi.nlm.nih.gov/pubmed/33238542
http://dx.doi.org/10.3390/jcm9113782

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