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From Inflammation to the Onset of Fibrosis through A(2A) Receptors in Kidneys from Deceased Donors

Pretransplant graft inflammation could be involved in the worse prognosis of deceased donor (DD) kidney transplants. A2A adenosine receptor (A(2A)R) can stimulate anti-inflammatory M2 macrophages, leading to fibrosis if injury and inflammation persist. Pre-implantation biopsies of kidney donors (47...

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Detalles Bibliográficos
Autores principales: Guillén-Gómez, Elena, Silva, Irene, Serra, Núria, Caballero, Francisco, Leal, Jesús, Breda, Alberto, San Martín, Rody, Pastor-Anglada, Marçal, Ballarín, José A., Guirado, Lluís, Díaz-Encarnación, Montserrat M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700266/
https://www.ncbi.nlm.nih.gov/pubmed/33233484
http://dx.doi.org/10.3390/ijms21228826