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Synthesis of Polycyclic Ether-Benzopyrans and In Vitro Inhibitory Activity against Leishmania tarentolae

Construction of a focused library of polycyclic ether-benzopyrans was undertaken in order to discover new therapeutic compounds that affect Leishmania growth and infectivity. This is especially of interest since there are few drug therapies for leishmaniasis that do not have serious drawbacks such h...

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Detalles Bibliográficos
Autores principales: Singh, Sarita, Grabowski, Jacob P., Pohani, Shilpa, Apuzzo, C. Fiore, Platt, David C., Jones, Marjorie A., Mitchell, T. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700287/
https://www.ncbi.nlm.nih.gov/pubmed/33233418
http://dx.doi.org/10.3390/molecules25225461