Differential Effects of 1α,25-Dihydroxyvitamin D(3) on the Expressions and Functions of Hepatic CYP and UGT Enzymes and Its Pharmacokinetic Consequences In Vivo

The compound 1α,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) is the active form of vitamin D(3) and a representative ligand of the vitamin D receptor (VDR). Previous studies have described the impacts of 1,25(OH)(2)D(3) on a small number of cytochrome P450 (CYP) and uridine diphosphate-glucuronyltrans...

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Detalles Bibliográficos
Autores principales: Doan, Trang Nguyen Kieu, Vo, Dang-Khoa, Kim, Hyojung, Balla, Anusha, Lee, Yunjong, Yoon, In-Soo, Maeng, Han-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700423/
https://www.ncbi.nlm.nih.gov/pubmed/33238436
http://dx.doi.org/10.3390/pharmaceutics12111129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700423/
https://www.ncbi.nlm.nih.gov/pubmed/33238436
http://dx.doi.org/10.3390/pharmaceutics12111129

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