Cerebellum-Specific Deletion of the GABA(A) Receptor δ Subunit Leads to Sex-Specific Disruption of Behavior

Granule cells (GCs) of the cerebellar input layer express high-affinity δ GABA(A) subunit-containing GABA(A) receptors (δGABA(A)Rs) that respond to ambient GABA levels and context-dependent neuromodulators like steroids. We find that GC-specific deletion of δGABA(A) (cerebellar [cb] δ knockout [KO])...

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Detalles Bibliográficos
Autores principales: Rudolph, Stephanie, Guo, Chong, Pashkovski, Stan L., Osorno, Tomas, Gillis, Winthrop F., Krauss, Jeremy M., Nyitrai, Hajnalka, Flaquer, Isabella, El-Rifai, Mahmoud, Datta, Sandeep Robert, Regehr, Wade G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700496/
https://www.ncbi.nlm.nih.gov/pubmed/33147470
http://dx.doi.org/10.1016/j.celrep.2020.108338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700496/
https://www.ncbi.nlm.nih.gov/pubmed/33147470
http://dx.doi.org/10.1016/j.celrep.2020.108338

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