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Self-Nanoemulsifying System Loaded with Sildenafil Citrate and Incorporated within Oral Lyophilized Flash Tablets: Preparation, Optimization, and In Vivo Evaluation

Sildenafil citrate is a drug used throughout the world primarily to treat erectile dysfunction. Several problems with the commercially available product decrease its efficacy, such as limited solubility, delayed onset of action, and low bioavailability with a large variability in the absorption prof...

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Detalles Bibliográficos
Autores principales: Hosny, Khaled M., Alhakamy, Nabil A., Almodhwahi, Maeen A., Kurakula, Mallesh, Almehmady, Alshaimaa M., Elgebaly, Samar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700536/
https://www.ncbi.nlm.nih.gov/pubmed/33233372
http://dx.doi.org/10.3390/pharmaceutics12111124