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Phase I/II Clinical Trial of the Anti-Podoplanin Monoclonal Antibody Therapy in Dogs with Malignant Melanoma

Podoplanin (PDPN), a small transmembrane mucin-like glycoprotein, is ectopically expressed on tumor cells. PDPN is known to be linked with several aspects of tumor malignancies in certain types of human and canine tumors. Therefore, it is considered to be a novel therapeutic target. Monoclonal antib...

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Detalles Bibliográficos
Autores principales: Kamoto, Satoshi, Shinada, Masahiro, Kato, Daiki, Yoshimoto, Sho, Ikeda, Namiko, Tsuboi, Masaya, Yoshitake, Ryohei, Eto, Shotaro, Hashimoto, Yuko, Takahashi, Yosuke, Chambers, James, Uchida, Kazuyuki, Kaneko, Mika K., Fujita, Naoki, Nishimura, Ryohei, Kato, Yukinari, Nakagawa, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700559/
https://www.ncbi.nlm.nih.gov/pubmed/33238582
http://dx.doi.org/10.3390/cells9112529