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Phase I/II Clinical Trial of the Anti-Podoplanin Monoclonal Antibody Therapy in Dogs with Malignant Melanoma
Podoplanin (PDPN), a small transmembrane mucin-like glycoprotein, is ectopically expressed on tumor cells. PDPN is known to be linked with several aspects of tumor malignancies in certain types of human and canine tumors. Therefore, it is considered to be a novel therapeutic target. Monoclonal antib...
Autores principales: | Kamoto, Satoshi, Shinada, Masahiro, Kato, Daiki, Yoshimoto, Sho, Ikeda, Namiko, Tsuboi, Masaya, Yoshitake, Ryohei, Eto, Shotaro, Hashimoto, Yuko, Takahashi, Yosuke, Chambers, James, Uchida, Kazuyuki, Kaneko, Mika K., Fujita, Naoki, Nishimura, Ryohei, Kato, Yukinari, Nakagawa, Takayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700559/ https://www.ncbi.nlm.nih.gov/pubmed/33238582 http://dx.doi.org/10.3390/cells9112529 |
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