Clinical Perspectives of ERCC1 in Bladder Cancer

ERCC1 is a key regulator of nucleotide excision repair (NER) pathway that repairs bulky DNA adducts, including intrastrand DNA adducts and interstrand crosslinks (ICLs). Overexpression of ERCC1 has been linked to increased DNA repair capacity and platinum resistance in solid tumors. Multiple single...

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Detalles Bibliográficos
Autores principales: Koutsoukos, Konstantinos, Andrikopoulou, Angeliki, Dedes, Nikos, Zagouri, Flora, Bamias, Aristotelis, Dimopoulos, Meletios-Athanasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700570/
https://www.ncbi.nlm.nih.gov/pubmed/33266377
http://dx.doi.org/10.3390/ijms21228829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700570/
https://www.ncbi.nlm.nih.gov/pubmed/33266377
http://dx.doi.org/10.3390/ijms21228829

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