Synthesis, Kinetic and Conformational Studies of 2-Substituted-5-(β-d-glucopyranosyl)-pyrimidin-4-ones as Potential Inhibitors of Glycogen Phosphorylase

Dysregulation of glycogen phosphorylase, an enzyme involved in glucose homeostasis, may lead to a number of pathological states such as type 2 diabetes and cancer, making it an important molecular target for the development of new forms of pharmaceutical intervention. Based on our previous work on t...

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Detalles Bibliográficos
Autores principales: Mavreas, Konstantinos F., Neofytos, Dionysios D., Chrysina, Evangelia D., Venturini, Alessandro, Gimisis, Thanasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700572/
https://www.ncbi.nlm.nih.gov/pubmed/33266408
http://dx.doi.org/10.3390/molecules25225463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700572/
https://www.ncbi.nlm.nih.gov/pubmed/33266408
http://dx.doi.org/10.3390/molecules25225463

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