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Synthesis, Kinetic and Conformational Studies of 2-Substituted-5-(β-d-glucopyranosyl)-pyrimidin-4-ones as Potential Inhibitors of Glycogen Phosphorylase

Dysregulation of glycogen phosphorylase, an enzyme involved in glucose homeostasis, may lead to a number of pathological states such as type 2 diabetes and cancer, making it an important molecular target for the development of new forms of pharmaceutical intervention. Based on our previous work on t...

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Detalles Bibliográficos
Autores principales:	Mavreas, Konstantinos F., Neofytos, Dionysios D., Chrysina, Evangelia D., Venturini, Alessandro, Gimisis, Thanasis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700572/ https://www.ncbi.nlm.nih.gov/pubmed/33266408 http://dx.doi.org/10.3390/molecules25225463

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