The Small GTPase RAC1B: A Potent Negative Regulator of-and Useful Tool to Study-TGFβ Signaling

SIMPLE SUMMARY: Transforming growth factor β (TGFβ) promotes pancreatic ductal adenocarcinoma (PDAC) primarily through its non-canonical (non-Smad) signaling arms, including signaling by the small GTPase RAC1. The human RAC1 gene also encodes for another protein, designated RAC1B, but whether this i...

Descripción completa

Detalles Bibliográficos
Autores principales: Ungefroren, Hendrik, Wellner, Ulrich F., Keck, Tobias, Lehnert, Hendrik, Marquardt, Jens-Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700615/
https://www.ncbi.nlm.nih.gov/pubmed/33266416
http://dx.doi.org/10.3390/cancers12113475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700615/
https://www.ncbi.nlm.nih.gov/pubmed/33266416
http://dx.doi.org/10.3390/cancers12113475

Ejemplares similares