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Metagenomic Information Recovery from Human Stool Samples Is Influenced by Sequencing Depth and Profiling Method

Sequencing of the 16S rRNA gene (16S) has long been a go-to method for microbiome characterization due to its accessibility and lower cost compared to shotgun metagenomic sequencing (SMS). However, 16S sequencing rarely provides species-level resolution and cannot provide direct assessment of other...

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Detalles Bibliográficos
Autores principales: Santiago-Rodriguez, Tasha M., Garoutte, Aaron, Adams, Emmase, Nasser, Waleed, Ross, Matthew C., La Reau, Alex, Henseler, Zachariah, Ward, Tonya, Knights, Dan, Petrosino, Joseph F., Hollister, Emily B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700633/
https://www.ncbi.nlm.nih.gov/pubmed/33233349
http://dx.doi.org/10.3390/genes11111380