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Metagenomic Information Recovery from Human Stool Samples Is Influenced by Sequencing Depth and Profiling Method
Sequencing of the 16S rRNA gene (16S) has long been a go-to method for microbiome characterization due to its accessibility and lower cost compared to shotgun metagenomic sequencing (SMS). However, 16S sequencing rarely provides species-level resolution and cannot provide direct assessment of other...
Autores principales: | Santiago-Rodriguez, Tasha M., Garoutte, Aaron, Adams, Emmase, Nasser, Waleed, Ross, Matthew C., La Reau, Alex, Henseler, Zachariah, Ward, Tonya, Knights, Dan, Petrosino, Joseph F., Hollister, Emily B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700633/ https://www.ncbi.nlm.nih.gov/pubmed/33233349 http://dx.doi.org/10.3390/genes11111380 |
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