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TNF Is Partially Required for Cell-Death-Triggered Skin Inflammation upon Acute Loss of cFLIP
cFLIP is required for epidermal integrity and skin inflammation silencing via protection from TNF-induced keratinocyte apoptosis. Here, we generated and analyzed cFLIP epidermal KO mice with additional TNF deficiency. Intriguingly, the ablation of TNF rescued the pathological phenotype of epidermal...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700656/ https://www.ncbi.nlm.nih.gov/pubmed/33238518 http://dx.doi.org/10.3390/ijms21228859 |