Plasmin-Induced Activation of Human Platelets Is Modulated by Thrombospondin-1, Bona Fide Misfolded Proteins and Thiol Isomerases

Inflammatory processes are triggered by the fibrinolytic enzyme plasmin. Tissue-type plasminogen activator, which cleaves plasminogen to plasmin, can be activated by the cross-β-structure of misfolded proteins. Misfolded protein aggregates also represent substrates for plasmin, promoting their degra...

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Detalles Bibliográficos
Autores principales: Pielsticker, Claudia, Brodde, Martin F., Raum, Lisa, Jurk, Kerstin, Kehrel, Beate E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700677/
https://www.ncbi.nlm.nih.gov/pubmed/33238433
http://dx.doi.org/10.3390/ijms21228851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700677/
https://www.ncbi.nlm.nih.gov/pubmed/33238433
http://dx.doi.org/10.3390/ijms21228851

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