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HIF-1α-Dependent Induction of Carboxypeptidase A4 and Carboxypeptidase E in Hypoxic Human Adipose-Derived Stem Cells

Hypoxia induces the expression of several genes through the activation of a master transcription factor, hypoxia-inducible factor (HIF)-1α. This study shows that hypoxia strongly induced the expression of two carboxypeptidases (CP), CPA4 and CPE, in an HIF-1α-dependent manner. The hypoxic induction...

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Detalles Bibliográficos
Autores principales: Moon, Yunwon, Moon, Ramhee, Roh, Hyunsoo, Chang, Soojeong, Lee, Seongyeol, Park, Hyunsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700838/
https://www.ncbi.nlm.nih.gov/pubmed/33203807
http://dx.doi.org/10.14348/molcells.2020.0100