Cargando…

Allithiamine Exerts Therapeutic Effects on Sepsis by Modulating Metabolic Flux during Dendritic Cell Activation

Recent studies have highlighted that early enhancement of the glycolytic pathway is a mode of maintaining the pro-inflammatory status of immune cells. Thiamine, a well-known co-activator of pyruvate dehydrogenase complex, a gatekeeping enzyme, shifts energy utilization of glucose from glycolysis to...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Eun Jung, Jeon, Chang Hyun, Park, Dong Ho, Kwon, Tae-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700841/
https://www.ncbi.nlm.nih.gov/pubmed/33243937
http://dx.doi.org/10.14348/molcells.2020.0198