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Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells

The mammalian BREAST CANCER 2 (BRCA2) gene is a tumor suppressor that plays a crucial role in DNA repair and homologous recombination (HR). Here, we report the identification and characterization of OsBRCA2, the rice orthologue of human BRCA2. Osbrca2 mutant plants exhibit normal vegetative growth b...

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Detalles Bibliográficos
Autores principales: Fu, Ruifeng, Wang, Chong, Shen, Hongyu, Zhang, Jie, Higgins, James D., Liang, Wanqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701097/
https://www.ncbi.nlm.nih.gov/pubmed/33304374
http://dx.doi.org/10.3389/fpls.2020.600820