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Adjuvanted Schistosoma mansoni-Cathepsin B With Sulfated Lactosyl Archaeol Archaeosomes or AddaVax™ Provides Protection in a Pre-Clinical Schistosomiasis Model

Schistosomiasis threatens 800 million people worldwide. Chronic pathology manifests as hepatosplenomegaly, and intestinal schistosomiasis caused by Schistosoma mansoni can lead to liver fibrosis, cirrhosis, and blood in the stool. To assist the only FDA-approved drug, praziquantel, in parasite elimi...

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Detalles Bibliográficos
Autores principales: Perera, Dilhan J., Hassan, Adam S., Jia, Yimei, Ricciardi, Alessandra, McCluskie, Michael J., Weeratna, Risini D., Ndao, Momar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701121/
https://www.ncbi.nlm.nih.gov/pubmed/33304354
http://dx.doi.org/10.3389/fimmu.2020.605288