Poly(ADP-Ribose) Polymerase Inhibitors in Prostate Cancer: Molecular Mechanisms, and Preclinical and Clinical Data

Genomic instability is one of the hallmarks of cancer. The incidence of genetic alterations in homologous recombination repair genes increases during cancer progression, and 20% of prostate cancers (PCas) have defects in DNA repair genes. Several somatic and germline gene alterations drive prostate...

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Detalles Bibliográficos
Autores principales: Sigorski, Dawid, Iżycka-Świeszewska, Ewa, Bodnar, Lubomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701127/
https://www.ncbi.nlm.nih.gov/pubmed/33044685
http://dx.doi.org/10.1007/s11523-020-00756-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701127/
https://www.ncbi.nlm.nih.gov/pubmed/33044685
http://dx.doi.org/10.1007/s11523-020-00756-4

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