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SCCNV: A Software Tool for Identifying Copy Number Variation From Single-Cell Whole-Genome Sequencing

Identification of de novo copy number variations (CNVs) across the genome in single cells requires single-cell whole-genome amplification (WGA) and sequencing. Although many experimental protocols of amplification methods have been developed, all suffer from uneven distribution of read depth across...

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Detalles Bibliográficos
Autores principales: Dong, Xiao, Zhang, Lei, Hao, Xiaoxiao, Wang, Tao, Vijg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701142/
https://www.ncbi.nlm.nih.gov/pubmed/33304377
http://dx.doi.org/10.3389/fgene.2020.505441