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Inhibition of BRD4 triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells

Oesophageal cancer is one of the most frequent solid malignancies and the leading cause of cancer‐related death around the world. It is urgent to develop novel therapy strategies to improve patient outcomes. Acetylation modification of histones has been extensively studied in epigenetics. BRD4, a re...

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Detalles Bibliográficos
Autores principales: Xu, Jian‐Ling, Yuan, Ya‐Jiao, Lv, Jiao, Qi, Di, Wu, Meng‐Di, Lan, Jing, Liu, Sheng‐Nan, Yang, Yong, Zhai, Jing, Jiang, Han‐Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701500/
https://www.ncbi.nlm.nih.gov/pubmed/32954665
http://dx.doi.org/10.1111/jcmm.15901