A novel danshensu derivative ameliorates experimental colitis by modulating NADPH oxidase 4‐dependent NLRP3 inflammasome activation

We have previously reported a novel compound [4‐(2‐acetoxy‐3‐((R)‐3‐(benzylthio)‐1‐methoxy‐1‐oxopropan‐2‐ylamino)‐3‐oxopropyl)‐1,2‐phenylene diacetate (DSC)], derived from danshensu, exhibits cytoprotective activities in vitro. Here, we investigated the effects and underlying mechanisms of DSC on de...

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Detalles Bibliográficos
Autores principales: Pan, Li‐Long, Ren, Zhengnan, Liu, Yanyan, Zhao, Yalei, Li, Hongli, Pan, Xiaohua, Fang, Xin, Liang, Wenjie, Wang, Yang, Yang, Jun, Sun, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701520/
https://www.ncbi.nlm.nih.gov/pubmed/32945118
http://dx.doi.org/10.1111/jcmm.15890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701520/
https://www.ncbi.nlm.nih.gov/pubmed/32945118
http://dx.doi.org/10.1111/jcmm.15890

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