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Activating Nrf2 signalling alleviates osteoarthritis development by inhibiting inflammasome activation

Osteoarthritis (OA), which is characterized by proliferation of subchondral bone and the degeneration of articular cartilage, is the most prevalent human arthritis. Nod‐like receptor pyrin domain 3 (NLRP3) inflammasome is a hot spot in recent year and has been reported to be associated with OA synov...

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Detalles Bibliográficos
Autores principales: Yan, Zijian, Qi, Weihui, Zhan, Jingdi, Lin, Zeng, Lin, Jian, Xue, Xinghe, Pan, Xiaoyun, Zhou, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701566/
https://www.ncbi.nlm.nih.gov/pubmed/32965793
http://dx.doi.org/10.1111/jcmm.15905