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Dual deficiency of angiotensin‐converting enzyme‐2 and Mas receptor enhances angiotensin II‐induced hypertension and hypertensive nephropathy

Angiotensin‐converting enzyme‐2 (ACE2) and Mas receptor are the major components of the ACE2/Ang 1‐7/Mas axis and have been shown to play a protective role in hypertension and hypertensive nephropathy individually. However, the effects of dual deficiency of ACE2 and Mas (ACE2/Mas) on Ang II‐induced...

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Detalles Bibliográficos
Autores principales: Ni, Jun, Yang, Fuye, Huang, Xiao‐Ru, Meng, Jinxiu, Chen, Jiaoyi, Bader, Michael, Penninger, Josef M., Fung, Erik, Yu, Xue‐Qing, Lan, Hui‐Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701568/
https://www.ncbi.nlm.nih.gov/pubmed/32971570
http://dx.doi.org/10.1111/jcmm.15914