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LncRNA ARAP1‐AS2 promotes high glucose‐induced human proximal tubular cell injury via persistent transactivation of the EGFR by interacting with ARAP1

The persistent transactivation of epidermal growth factor receptor (EGFR) causes subsequent activation of the TGF‐β/Smad3 pathway, which is closely associated with fibrosis and cell proliferation in diabetic nephropathy (DN), but the exact mechanism of persistent EGFR transactivation in DN remains u...

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Detalles Bibliográficos
Autores principales: Li, Xin, Ma, Tian‐Kui, Wen, Si, Li, Lu‐Lu, Xu, Li, Zhu, Xin‐Wang, Zhang, Cong‐Xiao, Liu, Nan, Wang, Xu, Fan, Qiu‐Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701572/
https://www.ncbi.nlm.nih.gov/pubmed/32969198
http://dx.doi.org/10.1111/jcmm.15897