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A disintegrin and metalloproteinase 8 induced epithelial‐mesenchymal transition to promote the invasion of colon cancer cells via TGF‐β/Smad2/3 signalling pathway

A disintegrin and metalloproteinase 8 (ADAM8) protein is a multi‐domain transmembrane glycoprotein which involves in extracellular matrix remodelling, cell adhesion, invasion and migration. ADAM8 and epithelial‐mesenchymal transition (EMT) play an important role in tumour invasion has been well esta...

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Detalles Bibliográficos
Autores principales: Jin, Qianna, Jin, Xin, Liu, Tao, Lu, Xiaoming, Wang, Guobin, He, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701584/
https://www.ncbi.nlm.nih.gov/pubmed/32954649
http://dx.doi.org/10.1111/jcmm.15907